Description
Genomics is the study of the genome and the human genome is a highly complex arrangement of two sets of 23 chromosomes or DNA molecules. Some genes in humans are associated with health and disease. The treatment of any disease or infection starts with prior knowledge of the genome which is possible through genomics. It involves a technique that develops ways to diagnose and treat disease by understanding the way genes, proteins, and other cellular molecules work. Therefore, this book discusses the human genome, genes in human health and disease, methods to gene function analysis, Shotgun sequencing and its application to various genome projects, Algorithm for analysis of DNA and its complexity, Algorithm, and process for building a phylogenetic tree. Since this book deals with the human genome and infection, therefore, its some of the chapters describe virulent genes in infectious disease, in silico, and in vitro methods for the identification of antimicrobial resistance in the genome. A lot of infections are found on the globe, and it is not possible to write all infection in a single book, therefore, the author discussed expression and functional genomics for biomarker identification in Tuberculosis (most devastating infection) and last chapter describe Genomics based diagnostic methods for the analysis of COVID-19 which is a current global problem. Collectively this book would be a valuable and fundamental guide that conveys the knowledge needed to understand the abovementioned topic precisely. Contents 1. Human and Primate Genomes2. Genes in Human Health and Disease 2. Genes in Human Health and Disease 3. Methods of Gene Function Analysis 4. Shotgun Sequencing and its Application in Various Genome Projects 5. Algorithms for Analysis of DNA and its Complexity 6. Algorithms and Processes for Building a Phylogenetic Tree 7. Virulent Genes in Infectious Disease 8. In Silico and in Vitro Methods for Identification of Antimicrobial Resistance in The Genome 9. Expres.
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